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動物疾病現(xiàn)貨模型

Animal Disease Available
糖尿病及并發(fā)癥研究 肥胖及脂肪肝研究 心腦血管疾病研究 腫瘤與代謝研究 動物疾病現(xiàn)貨模型 動物表型檢測 分子生物學(xué)及病理檢測 其他疾病模型研究
飲食誘導(dǎo)肥胖小鼠模型
發(fā)布時間: 2022-05-02 瀏覽量:

項(xiàng)目介紹:


肥胖是導(dǎo)致高血壓、糖尿病、冠心病等多種慢性疾病發(fā)生的主要因素。通過高脂飲食誘導(dǎo)的肥胖模型,更好的模擬了人類疾病的發(fā)生發(fā)展過程,且模型構(gòu)建過程簡單,穩(wěn)定性好,并具有易操作、周期較短、可重復(fù)性高等有點(diǎn)。 


價格體系:


飲食誘導(dǎo)肥胖小鼠模型(圖1)


案例介紹:


飲食誘導(dǎo)肥胖小鼠模型(圖2)


Licochalcone A (LA) reduced body weight in high-fat diet (HFD)-induced obese mice. (A) Male mice were fed an HFD (containing 60% fat) for 16 weeks, and administered DMSO, 5 mg/kg licochalcone A (LA5), or 10 mg/kg licochalcone A (LA10) by intraperitoneal injection (I.P.) twice a week from week 4 to 16. (B) Weight gain was measured for 16 weeks. (C) The appearance of the animal and (D) weight gain measured in the last week. (E) Food intake monitored each day.


參考文獻(xiàn):

Protective Effects of Licochalcone A Ameliorates Obesity and Non-Alcoholic Fatty Liver Disease Via Promotion of the Sirt-1/AMPK Pathway in Mice Fed a High-Fat Diet.Cells 2019 05 11;8(5)